HP OpenVMS Guide to System Security > Appendix A Assigning Privileges

SETPRV Privilege (All)

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The SETPRV privilege lets the user's process create processes whose privileges are greater than its own either by executing the Create Process ($CREPRC) system service with an optional argument or by issuing the DCL command RUN to create a process. A process with this privilege can also execute the DCL command SET PROCESS/PRIVILEGES to obtain any desired privilege.

Exercise the same caution in granting SETPRV as in granting any other privilege because SETPRV lets a process enable any or all privileges.